Vehicle on fire after crashing into Melbourne's Bourke St Mall

The dramatic scene was captured by Twitter user @chrismacheras

Two other people have been injured amid reports of a shooting and stabbing in Bourke Street this afternoon.

Video posted to Twitter and broadcast on television showed a man repeatedly swinging an object at two police officers in the downtown area of the city.

A civilian can be seen pushing his shopping trolley at the attacker, which only momentarily stops the suspect from lashing his arm toward two police officers.

Witnesses say they saw the man drive a truck into the Target centre and as the auto caught fire he tried to fight and stab police and bystanders. "A third person has also been taken to hospital". Condition not yet known.

Officers said they were initially called to a vehicle fire around 4:20pm (AEDT).

The incident comes as a man is on trial for a 2017 attack on the same street which left six people dead.

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The suspect has been shot and is alive, police say.

Police shot a man who threatened officers with a knife and he is in a critical condition in hospital, Victoria Police Superintendent David Clayton said.

SBS News has contacted Victoria Police for comment.

'The exact circumstances are yet to be determined at this stage.

Police have also urged the public to avoid the Street after witnesses describe a vehicle bursting into flames.

"Police are not looking for anyone further at this early stage", police said in a statement.

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Another said they heard "what sounded like a bomb and gun shot".

Melbourne resident Meegan May tweeted: "Chaos in Bourkest as a guy seems to have set his auto on fire then attacking police with a knife".

Markel Villasin, 22, was finishing his shift at KFC on Bourke St as the drama unfolded.

'Police response was swift and overwhelming.

The Metropolitan Fire Brigade said the fire was contained within 10 minutes.

"I didn't know what was happening there was just so much chaos and screaming".

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Neil McKeller, who works at Hylands Bookshop on Bourke Street, told Guardian Australia he heard a loud explosion and then gunshots.

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