First baby born via uterus transplanted from dead donor

Baby born after womb transplant from dead donor

Brazilian doctors are reporting the world's first baby born to a woman who received a uterus transplanted from a deceased donor.

The first baby born from a woman who recieved a uterus transplant from a dead donor is healthy a year on. The deceased uterus donor was a 45-year old woman who died from a subarachnoid hemorrhage. In this case, a cesarean section was performed for birth at 35 weeks gestation, and along with the delivery of an nearly 6 pound healthy baby girl, the uterus was also removed.

With both the mother and baby healthy a year later, it represents a massive step forward for maternal science. Deceased donor uterus transplants have been attempted in the past few years, but none resulted in the birth of a healthy baby.

Dani Ejzenberg, a doctor at Brazil's Sao Paulo University hospital who led the research, said the transplant shows the technique is feasible and could offer women with uterine infertility access to a larger pool of potential donors. Last year, doctors at Baylor University Medical Center in Dallas delivered the first USA baby to be carried in a transplanted uterus.

The first birth after a womb transplant from a living donor took place in Sweden in September 2013.

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"There are still lots of things we don't understand about pregnancies, like how embryos implant", said Cesar Diaz, who co-authored an accompanying commentary in the journal.

Uterine transplantation is a multi-step process that requires coordination among numerous physicians.

While babies born from live donor uterus transplants have been done almost a dozen times before, including once in 2017 at Baylor Scott & White Hospital in Dallas, this birth marks the first time doctors have been able to remove the uterus from a recently deceased donor and have it result in a live birth.

The Brazilian woman did not have any pregnancy problems, Ejzenberg says, but he removed the uterus during the C-section because he wants to focus on helping more women have a single child rather than on one woman having more than one. "It is also a source of hope for those patients who [do not have a uterus] or who have lost it unexpectedly and do not have a family member or close friend to donate the uterus".

Researchers in Turkey performed a uterine transplant in 2011 from a deceased donor but have not had any successful pregnancies. Seven months after the transplant, doctors transferred an embryo made via in-vitro fertilization from the woman's egg and her husband's sperm into her womb.

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This breakthrough gives new hope to women with uterine factor infertility who can not conceive.

British expert Andrew Shennan, professor of obstetrics at King's College London, said: "Uterine transplant and subsequent pregnancies, including from live donors, have previously been reported, but this is the first case of a successful pregnancy from a deceased donor". However, a woman who received a live uterine transplant gave birth to a baby boy in 2017, making it a first for the U.S. The uterus was removed from recipient post that.

Five months after the transplant, the uterus showed no signs of rejection and the recipient was menstruating regularly. "There is the potential for uterus transplantation becoming mainstream".

Until recently, the only options available to women with so-called uterine infertility were adoption or the services of a surrogate mother.

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